NR2C2AP Antibody, HRP conjugated

Code CSB-PA016053LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NR2C2AP Polyclonal antibody
Uniprot No.
Target Names
NR2C2AP
Alternative Names
nr2c2ap antibody; NR2CA_HUMAN antibody; Nuclear receptor 2C2 associated protein antibody; Nuclear receptor 2C2-associated protein antibody; Repressor for TR4 transactivation antibody; TR4 orphan receptor associated 16 kDa protein antibody; TR4 orphan receptor associated protein TRA16 antibody; TR4 orphan receptor-associated 16 kDa protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nuclear receptor 2C2-associated protein (7-139AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
Gene References into Functions
  1. High TRA16 expression promotes small cell lung carcinoma by activating estrogen receptor beta and blocking testicular orphan nuclear receptor 2 PMID: 23129017
  2. TRA16 may function as a novel repressor to selectively suppress the TR4-mediated transactivation PMID: 12486131
  3. Together, these findings provide the first in vivo evidence that an orphan nuclear receptor, such as TR4, may play major roles in the RA-mediated apoptosis or differentiation in P19 cells. PMID: 15381082
  4. Taken together, these results suggested that TR4 should be one of important regulators of OXT gene expression. PMID: 17054912
Subcellular Location
Nucleus.
Protein Families
NR2C2AP family
Tissue Specificity
Expressed in all tissues examined, with highest expression in heart, skeletal muscle and pancreas.
Database Links

HGNC: 30763

OMIM: 608719

KEGG: hsa:126382

STRING: 9606.ENSP00000332823

UniGene: Hs.708153

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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